mySTEMspace

Apr 23, 2020 ... Targeting of the IL-6 pathway has led to innovative therapeutic approaches for various rheumatic diseases, such as rheumatoid arthritis, ...

May 20, 2020 ... T cells play a central role in immune responses to cancer. ... Image courtesy of the National Institute of Allergy and Infectious Diseases.

Mar 11, 2023 ... This highly specific nitrate-responsive genetic circuit allows non-invasive diagnosis of inflammation-related diseases. In addition to in vitro ...

Jul 7, 2021 ... Despite recent advances in targeting different diseases, tissues or cell ... Since then, three other CAR T cell therapies — axicabtagene ...

Dec 17, 2019 ... Chimeric antigen receptor (CAR) T cell therapy, the first approved ... and thus the efficacy of CAR T cell therapy in these diseases.

Feb 13, 2020 ... Here, we review three common treatment modalities used to target BCMA in ... CAR T-cell therapeutic agents including bb2121, NIH CAR-BCMA, ...

Jun 3, 2021 ... Interleukins and associated cytokines serve as the means of communication for innate and adaptive immune cells as well as non-immune cells ...

Apr 29, 2021 ... Increased understanding of disease biology over the years has led to parallel improvement in treatment modalities, evidenced by the emergence of ...

May 30, 2022 ... Cell-based therapy, which involves the administration of cells as living ... as treatment strategies tailored to specific diseases must ...

Jan 3, 2020 ... The preparation of functional CAR T cells requires several key steps (Fig. ... S. D. Systems biology of neurodegenerative diseases. Integr.